Coagulation factor XIII polymorphisms and cardiovascular disease

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منابع مشابه

Advances of Coagulation Factor XIII

OBJECTIVE To provide a comprehensive literature review on roles of coagulation factor XIII (FXIII) in coagulation, wound healing, neoplasm, bone metabolism, and pregnancy. DATA SOURCES All articles in PubMed with key words "Coagulation factor XIII", "wound", "leukemia", "tumor", "bone," and "pregnancy" with published date from 2001 to 2016 were included in the study. Frequently cited publicat...

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Specific Activity Normal Polymorphisms Are Associated With High or Low Factor XIII Genotype/Phenotype Correlations for Coagulation Factor XIII: Specific

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Inhibition of Fibrinolysis by Coagulation Factor XIII

The inhibitory effect of coagulation factor XIII (FXIII) on fibrinolysis has been studied for at least 50 years. Our insight into the underlying mechanisms has improved considerably, aided in particular by the discovery that activated FXIII cross-links α2-antiplasmin (α2AP) to fibrin. In this review, the most important effects of different cross-linking reactions on fibrinolysis are summarized....

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Immunological studies of coagulation factor XIII.

Human fibrin-stabilizing factor (Factor XIII) has been studied immunologically by the preparation of specific anti-Factor XIII antiserum in rabbits. On immunodiffusion it was found that normal plasma produced two precipitin lines. One of the precipitin lines was identical with that present in soluble platelet extract (the alpha-component), the other with that present in normal serum (beta-compo...

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Coagulation factor and protease pathways in thrombosis and cardiovascular disease.

The biochemical characterisation of the proteolytic pathways that constitute blood coagulation was one of the most relevant achievements in biomedical research during the second half of the 20th century. Understanding these pathways was of crucial importance for improving global health through application in haemostasis and thrombosis pathologies. Immediately after the cloning of the genes corr...

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ژورنال

عنوان ژورنال: Revista Clínica Escuela de Medicina UCR-HSJD

سال: 2013

ISSN: 2215-2741

DOI: 10.15517/rc_ucr-hsjd.v3i10.12809